Easy way to remove all network printers

I have about 2200 workstations, with a mixture of Bindery Queue and ADS
Print Server printers on them, and, I want to remove ALL network printers at
one fell swoop, and push them out using a new, geographical print setup.

I could do this with logon scripts, ZENWorks, or SMS 2003 (or even a simple
batch file), but am not sure on the best way to do this, so that there's no
issues with de-linked drivers or empty objects or anything--just need any
trace of the printers gone.

Is there any experience out there in doing this?

Thanks!