I installed ifolder 3.8 client on a new windows 7 home 64-bit pc and it worked fine until I ran windows up date.
Now I get a "Novell ifolder core has stopped working" message when ifolder tries to start.
I get the following information in the problem details.

At this point, ifolderapp.exe is running, but simias.exe is not.
It looks like simias is crashing when it starts.

I have removed and reinstalled the ifolder client at least three times, and the same result occurs.

This looks very similar to the problem reported earlier with XP SP3

Stopped working

Problem signature:
Problem Event Name: CLR20r3
Problem Signature 01: simias.exe
Problem Signature 02:
Problem Signature 03: 4ac4287b
Problem Signature 04: System.Web.Services
Problem Signature 05:
Problem Signature 06: 4a275f0d
Problem Signature 07: 276
Problem Signature 08: 42
Problem Signature 09: System.InvalidOperationException
OS Version: 6.1.7600.
Locale ID: 1033