I did not see this posted anywhere and thought it might be of interest.
Dr. Randy Pausch gave an inspiring "last lecture" at Carnegie Mellon in
September. He has been diagnosed with pancreatic cancer and will be
leaving his three little children behind. His lecture was originally a
speech to them, on himself and how to live their lives. His career
included extensive work with wearable computers, virtual reality and with
the Walt Disney Imagineering department, in addition to being a consultant
for companies such as Google. His projects included working on the design
and prototype testing of Aladdin's Magic Carpet Ride, Buzz Lightyear's
AstroBlaster and Virtual Pirates of the Carribean.

I've included the description from the Oprah show's website below. I found
the story to be quite powerful.

"Randy Pausch is a married father of three, a very popular professor at
Carnegie Mellon University and he is dying. He is suffering from
pancreatic cancer, which he says has returned after surgery, chemotherapy
and radiation. Doctors say he has only a few months to live.

In September 2007, Randy gave a final lecture to his students at Carnegie
Mellon that has since been downloaded more than a million times on the
Internet. "There's an academic tradition called the 'Last Lecture.'
Hypothetically, if you knew you were going to die and you had one last
lecture, what would you say to your students?" Randy says. "Well, for me,
there's an elephant in the room. And the elephant in the room, for me, it
wasn't hypothetical."

Despite the lecture's wide popularity, Randy says he really only intended
his words for his three small children. "I think it's great that so many
people have benefitted from this lecture, but the truth of the matter is
that I didn't really even give it to the 400 people at Carnegie Mellon who
came. I only wrote this lecture for three people, and when they're older,
they'll watch it," he says. "

The abridged version, which I found to be a pretty good intro, can be
found here (from the Oprah show):


The unabridged version (about 1:45:00) can be found here: