I am using a dat 72 and backing up about 43 gb total and it appears to
running out of space. I don't have compression on but I do have
GroupWise on the drive as well.

Is there something I need to do get the Dat 72 to do compression?
Strangly I seem to have the same issue on a Windows 2003 server using
Backupexec. No matter what settings we choose we don't seem to get