I installed 2 updates to my Windows 2003 server today and had to remove
them via safe mode. I'm not sure which one specifically was the problem
but after reboot it took a VERY long time for the server to come up and
though the https://server/zenworks page came up to a login, I was not
able to login. The http://server/zenworks-setup page would not come up
at all.

Upon removing these via safe mode, things were better again.