We've started testing Vista SP1 in our environment with ZCM 10.1.1.
I've installed Vista on two laptops and on both it is taking about 5
mins for the Zenworks Window (NALWIN) to load.
The notify icon appears to be working correctly as it refreshes and
displays up-to-date bundels and policies.

I have also installed Zenworks on two Vista SP1 desktop PCs and they
work as expected.

Any idea why the Zenworks Window is taking SO long to open on the laptops?