We have multiple GroupWise VM servers running 8.0.1 HP1 and are receiving several complaints about the performance of GroupWise. The CPU utilization is at about 50%, memory utilization is about 50%, but what stood out to me is that the CPU Wait time is, on average, at 30%. What is a good way to troubleshoot what is causing the CPU Wait time? Other Linux VMs seem to be performing fine.

GroupWise 8.0.1 HP1
200-300 Users per GW server
1-2 Post Offices per GW server

VMware hosts are pretty new and have six core opteron processors. Disk storage is SAN over Fiber.