Just thought I would post a note in case someone els ran into the same problem. When we migrated our GroupWise system to Suse Linux 10 we ran into a problem where our GWIA could not receive email. The sending MTA would get back a 554 error "Relay Access Denied". We spent hours checking our Relay rules and Internet Addressing but could find nothing wrong. In the end it turned out that by default the Linux Postfix email program was installed and running on port 25, therefor our GWIA could not. The "Relay Access Denied" message was coming from Postfix not GWIA.

See: Disabling Postfix coexistence with Gwia on Linux SMTP servers 0 221956497