I use Spiceworks as a help desk software for my company. Help tickets are auto generated by sending an email to help@company.com. I noticed that tickets were not being created when I sent emails from my iPhone and iPad.
I reported the problem as an issue with Spiceworks support. After viewing my logs, this was their response:

It looks like the problem is the "From" address - for some reason the device in this test has double-quoted the name. You should be able to resolve this easily by removing the quotes from the name (if they are configured on the mobile device), or possibly by making a change to the mailbox owner's name.

Would that be a quick/easy change?

Subject: Test21
Date: Mon, 20 Feb 2012 16:24:39 -0500
Message-ID: <4F4...B3@company.com>
From: ""User Name "" <user@company.com>
To: "Help Desk" <help@company.com>

Since we have no problems with anyone using the GroupWise client or Web Access. I could only think that the issue was related the datasync server. In conversing with the Spiceworks support they reported one other user having the same issue.
And yes the space after ""User Name "" is there although it is nowhere in any setup GW, DataSync, or the iOS devices.

Currently using GW 8.0.2 HP3 on Windows Server 2003
Datasync server is version 1.2 build 730