I have an existing 11.2 setup and i am migrating to a new domain. Doing this off line in a lab before putting up into production.
My ZCM certificate failed when I changed the domain name and so I followed a thread about creating a new CA and certificates and registering them. Worked great. BUT the only ongoing issue I have seen is that in Zenworks Image Bundles can't browse to the ZCM appliance from a win7 pc.
Cant browse the file system of the specified server:
com.novell.zenworks.datamodel.exceptions.InternalD ataModelException: java.lang.RuntimeException: javax.net.ssl.SSLHandshakeException: sun.security.validator.ValidatorExceptions: No trusted certificate found.

This feature did work perfectly on this server before the name change.
Other than this small issue the new certificates work all other aspects of ZCM that I have tested.